Neurocognitive functioning in parents of schizophrenia patients: Attentional and executive performance vary with genetic loading
详细信息 查看全文
- 作者：Svenja Schulze-Rauschenbacha ; Leonhard Lennertza ; Stephan Ruhrmannb ; Nadine Petrovskyc ; Ulrich Ettingerc ; Ralf Pukropb ; Jan Dreherb ; d ; Joachim Klosterkö ; tterb ; Wolfgang Maiera ; e ; Michael Wagnera ; e ; michael.wagner@ukb.uni-bonn.de" class="auth_mail" title="E-mail the corresponding author
- 关键词：Schizophrenia ; Endophenotype ; Parents ; Cognition ; Neuropsychology ; Genetics
- 刊名：Psychiatry Research
- 出版年：2015
- 出版时间：30 December 2015
- 年：2015
- 卷：230
- 期：3
- 页码：885-891
- 全文大小：288 K
文摘
- •
Parents of schizophrenia patients showed significant cognitive deficits.
- •
Cognitive dysfunctions differentiated parents with/without ancestral history of SCZ.
- •
Executive and attentional dysfunctions are strongly determined by genetic factors.
- •
These functions are most promising to study the functional role of genetic variants.