Direct Electrical Stimulation of the Human Entorhinal Region and Hippocampus Impairs Memory

详细信息    查看全文

• 作者：Joshua Jacobs¹ ; ¹² ; ^{joshua.jacobs@columbia.edu} ; Jonathan Miller¹ ; Sang Ah Lee¹ ; ² ; Tom Coffey³ ; Andrew J. Watrous¹ ; Michael R. Sperling⁴ ; Ashwini Sharan⁴ ; Gregory Worrell⁵ ; Brent Berry⁵ ; Bradley Lega⁶ ; Barbara C. Jobst⁷ ; Kathryn Davis⁸ ; Robert E. Gross⁹ ; Sameer A. Sheth¹⁰ ; Youssef Ezzyat¹¹ ; Sandhitsu R. Das⁸ ; Joel Stein⁸ ; Richard Gorniak⁴ ; Michael J. Kahana¹¹ ; Daniel S. Rizzuto¹¹
• 关键词：deep brain stimulation ; entorhinal cortex ; hippocampus ; navigation ; memory ; theta oscillation
• 刊名：Neuron
• 出版年：2016
• 出版时间：7 December 2016
• 年：2016
• 卷：92
• 期：5
• 页码：983-990
• 全文大小：1722 K
• 卷排序：92

文摘

Deep brain stimulation in the entorhinal region and hippocampus impairs memory Stimulation at 50 Hz impairs both spatial and verbal memory encoding A causal role for the human medial temporal lobe in memory encoding is demonstrated