Fabrication and evaluation of chitosan/NaYF4:Yb3 +/Tm3 + upconversion nanoparticles composite beads based on the gelling of Pickering emulsion droplets
NaYF4:Yb3xA0;+/Tm3xA0;+ UCNPs were coated by F127 to improve aqueous dispersibility. NaYF4:Yb3xA0;+/Tm3xA0;+ UCNPs were assembled with chitosan to fabricate the composite beads (CMs). Pickering emulsions stabilized by UCNPs exhibited uniform and satisfactory emulsion droplets. The CMs prepared by the gelling of emulsion droplet preserved upconversion luminescent property. The resultant CMs showed good drug-loading capacity, release performance and biocompatibility.