Do randomized clinical trial selection criteria reflect levels of risk as observed in a general population of acute myocardial infarction survivors? The PEGASUS trial in the light of the FAST-MI 2005 registry
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- 作者：Etienne Puymirata ; etienne.puymirat@egp.aphp.fr" class="auth_mail" title="E-mail the corresponding author ; Franç ; ois Schieleb ; Marianne Zellerc ; Laurent Jacquemind ; Florence Leclercqe ; Xavier Marcaggif ; Jean Ferriè ; resg ; Tabassome Simonh ; Nicolas Danchina ; for the FAST-MI investigators
- 关键词：Acute myocardial infarction ; Antiplatelet therapy ; Coronary artery disease ; Reperfusion therapy ; ST-elevation myocardial infarction
- 刊名：International Journal of Cardiology
- 出版年：2016
- 出版时间：15 November 2016
- 年：2016
- 卷：223
- 期：Complete
- 页码：604-610
- 全文大小：600 K
文摘
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We investigated the PEGASUS-TIMI 54 trial criteria in a real life post-MI population.
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Patients were categorized according to criteria used in PEGASUS trial.
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We used data from a nationwide French registry including 3670 patients (FAST-MI).
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Enrichment criteria used in PEGAGUS succeed in defining a high-risk population.
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Age represents the most discriminant factor.