Immuno-modulating properties of saliphenylhalamide, SNS-032, obatoclax, and gemcitabine
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- 作者：Sandra Sö ; derholma ; b ; Maria Anastasinac ; Mohammad Majharul Islamc ; Janne Tynelld ; Minna M. Poranene ; Dennis H. Bamforda ; e ; Jakob Stenmanf ; Ilkka Julkunend ; g ; Ingrida &Scaron ; aulienėh ; Jef K. De Brabanderi ; Sampsa Matikainenb ; Tuula A. Nymana ; Xavier Saelensj ; k ; Denis Kainovc ; g ; denis.kainov@helsinki.fi" class="auth_mail" title="E-mail the corresponding author
- 关键词：Influenza A virus ; Antiviral agents ; Innate immunity ; Immune responses ; Virus-host interaction
- 刊名：Antiviral Research
- 出版年：2016
- 出版时间：February 2016
- 年：2016
- 卷：126
- 期：Complete
- 页码：69-80
- 全文大小：2767 K
文摘
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Several anti-IAV drugs are available and dozens are in development.
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We developed method for analysis of immuno-modulating properties of anti-IAV agents.
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Gemcitabine, but not SaliPhe, SNS-032 and obatoclax allowed activation of immune responses.
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Gemcitabine may protect infected patients against co- and re-infections.