Comparative effectiveness of flomoxef versus carbapenems in the treatment of bacteraemia due to extended-spectrum β-lactamase-producing Escherichia coli or Klebsiella pneumoniae with emphasis on minimum inhibitory concentration of flomoxef: a retrospective study
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- 作者：Chen-Hsiang Leea ; b ; lee900@adm.cgmh.org.tw" class="auth_mail" title="E-mail the corresponding author ; Lin-Hui Suc ; d ; Fang-Ju Chena ; Ya-Feng Tange ; Chia-Chin Lie ; Chun-Chih Chiene ; Jien-Wei Liua ; b
- 关键词：Cephamycins ; Outcome ; Mortality ; Enterobacteriaceae ; Propensity score matching ; Case&ndash ; control study
- 刊名：International Journal of Antimicrobial Agents
- 出版年：2015
- 出版时间：December 2015
- 年：2015
- 卷：46
- 期：6
- 页码：610-615
- 全文大小：540 K
文摘
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We compared the outcomes of patients with bacteraemia due to ESBL-producers.
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We discuss the implications of ESBL-producers with different flomoxef MICs.
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A suboptimal clinical outcome is anticipated when flomoxef is given.
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Flomoxef is suggested for bacteraemia due to ESBL-producing isolates with a MICflomoxef ≤1 mg/L.