Ankyrin exposure induced by activated protein kinase C plays a potential role in erythrophagocytosis
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- 作者：Fuzhou Tang ; Yang Ren ; Ruofeng Wang ; Xiaofeng Lei ; Xueru Deng ; Yajin Zhao ; Dong Chen ; Xiang Wang ; xwangchn@vip.sina.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Human erythrocytes ; Protein kinase C ; Calcium influx ; Phosphorylation of membrane proteins ; Ankyrin exposure ; Erythrophagocytosis
- 刊名：Biochimica et Biophysica Acta (BBA) - General Subjects
- 出版年：2016
- 出版时间：January 2016
- 年：2016
- 卷：1860
- 期：1
- 页码：120-128
- 全文大小：1139 K
文摘
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PMA induces ankyrin exposure on the erythrocyte surface and erythrophagocytosis.
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Calcium internalization is required for ankyrin exposure.
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Phosphorylation of membrane proteins is required for ankyrin exposure.
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Calcium internalization and protein phosphorylation induce ankyrin exposure.