Effect of the duplex length on the sensing performance of a displacement-based electrochemical nucleic acid sensor with an adjustable point mutation discrimination function
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- 作者：Fengqin LiaAuthor Vitae ; Yanmei XuaAuthor Vitae ; Xiang YubAuthor Vitae ; Zhigang Yua ; yzgyhdzm@126.com" class="auth_mail" title="E-mail the corresponding authorAuthor Vitae ; Hongrui JiaAuthor Vitae ; Yongbin SongaAuthor Vitae ; Hong YanaAuthor Vitae ; Guiling Zhanga ; Zhangguiling1969@126.com" class="auth_mail" title="E-mail the corresponding authorAuthor Vitae
- 关键词：Electrochemical sensor ; Nucleic acid sequence ; Point mutation discrimination ; Methylene blue
- 刊名：Sensors & Actuators: B. Chemical
- 出版年：2016
- 出版时间：29 October 2016
- 年：2016
- 卷：234
- 期：Complete
- 页码：648-657
- 全文大小：1895 K
文摘
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This versatile sensing method was developed for the detection of a designated specific DNA sequence.
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The study focuses on the effect of the duplex length on the sensing performance.
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The proposed sensor features a high specificity with the excellent adjustability.