Quantitative analysis of the endogenous GHB level in the hair of the Chinese population using GC/MS/MS
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- 作者：Yan Shi ; Xiaopei Cui ; Min Shen ; a ; minshensfjd@hotmail.com" class="auth_mail" title="E-mail the corresponding author ; Ping Xiang ; a ; xiangping2630@163.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Hair ; Endogenous ; GHB ; Forensic toxicology ; Gas chromatography-tandem mass spectrometry
- 刊名：Journal of Forensic and Legal Medicine
- 出版年：2016
- 出版时间：April 2016
- 年：2016
- 卷：39
- 期：Complete
- 页码：10-15
- 全文大小：799 K
文摘
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A method capable of quantifying endogenous GHB level in hair sample was developed and validated.
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The mean measured concentration of GHB level for 0–3 cm hair was 1.93 ± 1.40 ng/mg (n = 66).
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The endogenous GHB level in the hair of males was significantly higher than the level of females.
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Due to the wide distribution of endogenous GHB, it is hard to make a reasonable “cut off” in hair.