Intra-articular injection of Botulinum toxin A reduces neurogenic inflammation in CFA-induced arthritic rat model

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• 作者：Lin Wang^a ; Kaile Wang^b ; Xiao Chu^c ; Tieshan Li^a ; ^{tieshanl@126.com} ; Nana Shen^a ; Chenglei Fan^a ; Zhenyuan Niu^a ; Xiaochen Zhang^d ; Luoman Hu^a
• 关键词：Botulinum toxin A ; Rat model of chronic monoarthritis ; Neurogenic inflammation
• 刊名：Toxicon
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：126
• 期：Complete
• 页码：70-78
• 全文大小：2092 K
• 卷排序：126

文摘

Verified the anti-neurogenic inflammatory effect at the macroscopic and microcosmic level. BoNT/A may prevent the release of nociceptive nerve peptides and then suppresses the expression of inflammatory cytokines. Determined that it is unclear whether BoNT/A exhibits anti-inflammatory properties that have a direct effect.