Cross-clade protective immune responses of NS1-truncated live attenuated H5N1 avian influenza vaccines
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文摘

A 70-aa amino-terminal fragment of NS1 is long enough for viral replication.

CEF infected with NS1-truncated viruses expressed significant higher IFN-β levels.

The S-HALo/NS73 could provide effective homologous and heterologous protection.

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