Transcutaneous auricular vagus nerve stimulation regulates expression of growth differentiation factor 11 and activin-like kinase 5 in cerebral ischemia/reperfusion rats
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- 作者：Jingxi Ma ; Lina Zhang ; Guoqian He ; Xiaodan Tan ; Xinhao Jin ; Changqing Li ; macksoft1980@sina.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：ANOVA ; analysis of variance ; ABP ; arterial blood pressure ; ALK5 ; activin-like kinase 5 ; cVNS ; cervical vagus nerve stimulation ; CCA ; common carotid artery ; d ; day/days ; ECs ; endothelial cells ; EPCs ; endothelial progenitor cells ; ELISA ; enzyme linked immunosorbent assay ; ECA ; external carotid artery ; GDF11 ; growth differentiation factor 11 ; GAPDH ; glyceraldehyde 3-phosphate dehydrogenase ; HR ; heart rate ; h ; hour/hours ; ICA ; internal carotid artery ; I/R ; ischemia/reperfusion ; LSD ; least significan
- 刊名：Journal of the Neurological Sciences
- 出版年：2016
- 出版时间：15 October 2016
- 年：2016
- 卷：369
- 期：Complete
- 页码：27-35
- 全文大小：2571 K
文摘
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Expression of GDF11 increases in plasma and the cortex of cerebral I/R rats.
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Splenic GDF11 decreases in cerebral I/R rats.
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ALK5 is expressed in brain capillary ECs in cerebral I/R rats.
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ta-VNS regulates GDF11/ALK5 and induces angiogenesis in cerebral I/R rats.