Review of the synthesis and stability of low-symmetry 2D materials. Anisotropic transport properties of low-symmetry 2D materials and their applications in electronic devices. Anisotropic optical properties of low-symmetry 2D materials and their applications in photonic devices. Phonon properties and Raman spectroscopy of low symmetry 2D materials. New opportunities offered by these materials for piezoelectric devices. The prospects for their applications in thermoelectrics.