Drosophila eye developmental defect caused by elevation of the activity of the LIM-homeodomain protein, Lmx1a, requires its association with the Co-activator Chip
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- 作者：Ping Wang1 ; Yan Chen1 ; Chaojie Li ; Runan Zhao ; Feng Wang ; Xiaohui Lin ; Lei Cao ; Shanshan Li ; Liangchang Hu ; Yang Gao ; Yuanpei Li ; Shian Wu ; wusa@nankai.edu.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：dLmx1a ; LIM-HD ; Chip ; Eya ; Drosophila
- 刊名：Biochemical and Biophysical Research Communications
- 出版年：2016
- 出版时间：29 January 2016
- 年：2016
- 卷：470
- 期：1
- 页码：29-34
- 全文大小：2218 K
文摘
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Chip is a bona fide partner of dLmx1a in Drosophila eye development.
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Chip bridges two dLmx1a proteins to form a functional tetrameric complex.
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dLmx1a alters cell differentiation through repressing eya and stg expression.