Prediction of human protein-protein interaction by a domain-based approach
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- 作者：Xiaopan Zhanga ; Xiong Jiaoa ; jiaoxiong@tyut.edu.cn" class="auth_mail" title="E-mail the corresponding author ; Jie Songa ; Shan Changb
- 关键词：Optimizing model ; Predicting ; Domain&ndash ; domain interaction ; Method ; Network graph
- 刊名：Journal of Theoretical Biology
- 出版年：2016
- 出版时间：7 May 2016
- 年：2016
- 卷：396
- 期：Complete
- 页码：144-153
- 全文大小：3123 K
文摘
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A decent model for predicting PPIs was built via the information of PPIs and DDIs.
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The confidence probability was used for measuring the likelihood of the PPI.
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With using our predicting model we obtained 113 new probable PPIs.
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We constructed PPI network graphs to identify intriguing signal pathways.