Analysis on the preference for sequence matching between mRNA sequences and the corresponding introns in ribosomal protein genes
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- 作者：Qiang Zhanga ; Hong Lia ; ndlihong@imu.edu.cn" class="auth_mail" title="E-mail the corresponding author ; Xiaoqing Zhaob ; Yan Zhenga ; Hu Menga ; Yun Jiaa ; Hui Xuec ; Sulin Boa
- 关键词：Ribosomal protein genes ; MRNA sequences ; Introns ; Local matched alignment ; Optimal matched segments
- 刊名：Journal of Theoretical Biology
- 出版年：2016
- 出版时间：7 March 2016
- 年：2016
- 卷：392
- 期：Complete
- 页码：113-121
- 全文大小：977 K
文摘
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We have given a propose that the sequence matching relation between mRNA sequences and corresponding post-spliced introns plays a significant role in the process of gene expression and regulation.
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Functional sites such as translation initiation and termination sites, exon–exon joints and EJC regions can be revealed by our method.
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EJC and introns have competitive and cooperative relations in the process of combining on mRNA sequences.
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Intron sequences and mature mRNA sequences are co-evolved and interactive to play their functions.