Reconstruction of a genome-scale metabolic model and in silico analysis of the polymalic acid producer Aureobasidium pullulans CCTCC M2012223

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• 作者：Jun Feng^a ; Jing Yang^a ; Xiaorong Li^a ; Meijin Guo^b ; Bochu Wang^c ; Shang-tian Yang^d ; Xiang Zou^a ; ^c ; ^{zhx1030@swu.edu.cn}
• 关键词：Biopolymers ; Metabolic engineering ; Pyruvate carboxylase ; Reducing equivalents
• 刊名：Gene
• 出版年：2017
• 出版时间：5 April 2017
• 年：2017
• 卷：607
• 期：Complete
• 页码：1-8
• 全文大小：1657 K
• 卷排序：607

文摘

A genome-scale metabolic model of A. pullulans (iZX637) was constructed. PMA yield with iZX637 was predicted in accordance with the experimental data. Pyruvate carboxylase is an important PMA synthesis target based on iZX637 analysis.