Serum microRNA181a: Correlates with the intracellular cytokine levels and a potential biomarker for acute graft-versus-host disease
详细信息 查看全文
- 作者：Linna Xie ; linnaxiea@163.com" class="auth_mail" title="E-mail the corresponding author ; Fang Zhou ; zhoufangzf3@sina.com" class="auth_mail" title="E-mail the corresponding author ; Ximin Liu ; Yuan Fang ; Zhe Yu ; Ningxia Song ; Fansheng Kong
- 关键词：GVHD ; graft-versus-host disease ; allo-PBSCT ; allogeneic peripheral blood stem cell transplantation ; OD ; optical density ; HD ; healthy donors ; ROC ; receiver-operating characteristic
- 刊名：Cytokine
- 出版年：2016
- 出版时间：September 2016
- 年：2016
- 卷：85
- 期：Complete
- 页码：37-44
- 全文大小：1157 K
文摘
- •
miR-181a level was increased in patients with aGVHD.
- •
IL-2, IL-17a and IL-22 were positively related to miR-181a in aGVHD patients.
- •
IL-13 was negatively correlated with miR-181a level in aGVHD patients.
- •
High miR-181a level may be related to severity and poor survival rate of aGVHD.
- •
miR-181a may be a potential biomarker for aGVHD diagnosis.