Intensive atorvastatin improves endothelial function and decreases ADP-induced platelet aggregation in patients with STEMI undergoing primary PCI: A single-center randomized controlled trial
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- 作者：Xiaorong Xu ; Yu Liu ; Kuibao Li ; Pan Wang ; Li Xu ; Zhongsu Yang ; Xinchun Yang ; yxc6229@126.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Intensive statin therapy ; ST-segment elevation myocardial infarction ; Primary percutaneous coronary intervention ; Endothelin ; Platelet aggregation
- 刊名：International Journal of Cardiology
- 出版年：2016
- 出版时间：1 November 2016
- 年：2016
- 卷：222
- 期：Complete
- 页码：467-472
- 全文大小：376 K
文摘
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Intensive treatment with atorvastatin significantly reduced ET-1 serum level.
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Intensive treatment with atorvastatin also achieved a greater reduction of MA-ADP.
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ET-1 serum levels were positively correlated with MA-ADP after Intensive treatment.
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Patients in intensive group appeared to suffer from less cardiovascular events.