Immunomodulatory effects of a polysaccharide purified from Lepidium meyenii Walp. on macrophages
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- 作者：Wei Wanga ; Ye Zoua ; Qian Lia ; Riwen Maob ; Xingjun Shaob ; Dun Jinc ; Daheng Zhenga ; Ting Zhaoc ; Huifen Zhub ; Lin Zhangb ; Liuqing Yangc ; yangliuqing@ujs.edu.cn" class="auth_mail" title="E-mail the corresponding author ; Xiangyang Wud ; wuxy@ujs.edu.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：Maca ; Polysaccharides ; Immunomodulatory ; Macrophage activation
- 刊名：Process Biochemistry
- 出版年：2016
- 出版时间：April 2016
- 年：2016
- 卷：51
- 期：4
- 页码：542-553
- 全文大小：2600 K
文摘
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A polysaccharide MP21 was purified and characterized from Maca.
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MP21 could significantly activate the RAW264.7.
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MP21 upregulated protein and gene expression of NO in RAW264.7.
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NF-κB activation was observed in MP21-induced RAW264.7.
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MP21 could be explored as a potential immunomodulator.