Population difference in the association of BDNF promoter methylation with mild cognitive impairment in the Xinjiang Uygur and Han populations
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- 作者：Wenjuan Maa ; 1 ; Xiaohui Zhoua ; 1 ; zhouxiaohui858@sina.com" class="auth_mail" title="E-mail the corresponding author ; Huihui Jib ; 1 ; Mei Luoa ; Guili Liub ; Jinyun Lib ; Qinwen Wangb ; wangqinwen@nbu.edu.cn" class="auth_mail" title="E-mail the corresponding author ; Shiwei Duanb ; duanshiwei@nbu.edu.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：Mild cognitive impairment ; DNA methylation ; BDNF ; Population difference
- 刊名：Psychiatry Research
- 出版年：2015
- 出版时间：30 October 2015
- 年：2015
- 卷：229
- 期：3
- 页码：926-932
- 全文大小：1443 K
文摘
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No association of BDNF methylation with MCI was found in either Uygur or Han Chinese populations.
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BDNF methylation levels of male Xinjiang Han MCI cases were higher than male Xinjiang Uygur MCI cases.
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BDNF methylation levels were significantly higher in Xinjiang Han Chinese in than Ningbo Han Chinese.
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The differences of populations and environments may affect levels of BDNF methylation.