Programming and Inheritance of Parental DNA Methylomes in Mammals
详细信息 查看全文
- 作者：Lu Wang1 ; 3 ; 9 ; Jun Zhang4 ; 9 ; Jialei Duan1 ; 9 ; Xinxing Gao4 ; 9 ; Wei Zhu1 ; 3 ; Xingyu Lu5 ; Lu Yang6 ; Jing Zhang1 ; Guoqiang Li1 ; 3 ; Weimin Ci2 ; Wei Li7 ; Qi Zhou7 ; Neel Aluru8 ; Fuchou Tang6 ; Chuan He5 ; Xingxu Huang4 ; xingxuhuang@mail.nju.edu.cn" class="auth_mail ; Jiang Liu1 ; liuj@big.ac.cn" class="auth_mail
- 刊名：Cell
- 出版年：8 May 2014
- 年：2014
- 卷：157
- 期：4
- 页码：979-991
- 全文大小：2600 K
文摘
- •
At least a significant proportion of maternal methylome is actively demethylated
- •
5hmC and 5fC exist in both maternal and paternal genome
- •
DNA demethylation is independent of the passive dilution of oxidized 5mC bases
- •
Classification of all the known ICRs into germ-line ICRs or somatic ICRs