Regulators in the DNA damage response
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- 作者：Yunhua Liu1 ; yliu15@mdanderson.org" class="auth_mail" title="E-mail the corresponding author ; Yujing Li1 ; yli22@mdanderson.org" class="auth_mail" title="E-mail the corresponding author ; Xiongbin Lu ; xlu2@mdanderson.org" class="auth_mail" title="E-mail the corresponding author
- 关键词：DNA damage response ; Posttranslational modification ; Noncoding RNA ; microRNA ; Long noncoding RNA
- 刊名：Archives of Biochemistry and Biophysics
- 出版年：2016
- 出版时间：15 March 2016
- 年：2016
- 卷：594
- 期：Complete
- 页码：18-25
- 全文大小：720 K
文摘
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DDR is a highly sophisticated machinery to limit deleterious consequences in the cell.
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PTMs are a critical layer of regulation to modulate the functional features of the DDR components.
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Noncoding RNAs, including miRNAs and lncRNAs, are involved in DDR signaling and DNA repair.