Inhibition of curcumin on myeloid-derived suppressor cells is requisite for controlling lung cancer
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- 作者：Dan Liua ; Ming Youa ; Yujun Xua ; Fanlin Lia ; Dongya Zhanga ; Xiujun Lia ; Yayi Houa ; b ; yayihou@nju.edu.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：Lung cancer ; Curcumin ; Myeloid-derived suppressor cells (MDSCs)
- 刊名：International Immunopharmacology
- 出版年：2016
- 出版时间：October 2016
- 年：2016
- 卷：39
- 期：Complete
- 页码：265-272
- 全文大小：1720 K
文摘
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Curcumin inhibits Lewis lung carcinoma (LLC) isogenic tumor growth and weight.
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Curcumin reduces the accumulation of MDSCs in the LLC isogenic tumor model.
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Curcumin inhibits the immunosuppressive function of MDSCs.
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Curcumin decreases the expression level of interleukin-6 in tumor-bearing mice.