The influence of concentration of inactivated Edwardsiella tarda bacterin and immersion time on antigen uptake and expression of immune-related genes in Japanese flounder (Paralichthys olivaceus)

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• 作者：Yang Du^a ; Xiaoqian Tang^a ; Xiuzhen Sheng^a ; Jing Xing^a ; Wenbin Zhan^a ; ^b ; ^{wbzhan@ouc.edu.cn}
• 关键词：Japanese flounder (Paralichthys olivaceus) ; Edwardsiella tarda ; Immersion vaccination ; Antigen uptake ; Gene expression
• 刊名：Microbial Pathogenesis
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：103
• 期：Complete
• 页码：19-28
• 全文大小：7068 K
• 卷排序：103

文摘

Vaccine concentration and bath time could influence the antigen uptaken and genes expression. The effect of immersion vaccination could be evaluated based on the amount of antigen uptaken. Gill is the main route entry for the inactivated E. tarda in immersion vaccination of flounder. The 108-60 treatment induced the highest levels of antigen uptaken and genes expression.