FOXK2 Elicits Massive Transcription Repression and Suppresses the Hypoxic Response and Breast Cancer Carcinogenesis
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- 作者：Lin Shan1 ; Xing Zhou1 ; Xinhua Liu1 ; Yue Wang1 ; Dongxue Su1 ; Yongqiang Hou1 ; Na Yu1 ; Chao Yang1 ; Beibei Liu1 ; Jie Gao1 ; Yang Duan1 ; Jianguo Yang2 ; Wanjin Li2 ; Jing Liang2 ; Luyang Sun2 ; Kexin Chen3 ; Chenghao Xuan1 ; Lei Shi1 ; Yan Wang1 ; Yongfeng Shang1 ; 2 ; 4 ; yshang@hsc.pku.edu.cn" class="auth_mail" title="E-mail the corresponding author
- 刊名：Cancer Cell
- 出版年：2016
- 出版时间：14 November 2016
- 年：2016
- 卷：30
- 期：5
- 页码：708-722
- 全文大小：5906 K
文摘
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FOXK2 is a transcription repressor
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FOXK2 is physically associated with multiple corepressor complexes
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FOXK2 and its associated corepressor complexes target the hypoxia pathway
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FOXK2 suppresses the growth and metastasis of breast cancer