Mitochondrial proteomic alterations caused by long-term low-dose copper exposure in mouse cortex

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• 作者：Xuemei Lin^a ; ^b ; Gang Wei^c ; Zhijun Huang^d ; Zhongsen Qu^e ; Xinfeng Huang^b ; Hua Xu^a ; ^{huax_mail@126.com} ; Jianjun Liu^b ; Zhixiong Zhuang^b ; Xifei Yang^b ; ^{xifeiyang@gmail.com}
• 关键词：Proteomics ; Mitochondria ; Copper ; Neurotoxicity
• 刊名：Toxicology Letters
• 出版年：2016
• 出版时间：30 November 2016
• 年：2016
• 卷：263
• 期：Complete
• 页码：16-25
• 全文大小：2961 K
• 卷排序：263

文摘

Copper caused abnormal expression of mitochondrial proteins in brains. Functional categories of the proteins affected by copper were revealed. GRP75/GRP78 may be the key players in copper neurotoxicity.