Methylation of miR-145a-5p promoter mediates adipocytes differentiation
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- 作者：Jingjing Dua ; 1 ; Xiao Chenga ; 1 ; Linyuan Shena ; Zhendong Tana ; Jia Luoa ; Xiaoqian Wua ; Chendong Liua ; Qiong Yangc ; Yanzhi Jiangb ; Guoqing Tanga ; Xuewei Lia ; Shunhua Zhanga ; zhangsh1919@163.com" class="auth_mail" title="E-mail the corresponding author ; Li Zhua ; zhuli7508@163.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：miR-145a-5p ; DNA methylation ; Differentiation ; Proliferation
- 刊名：Biochemical and Biophysical Research Communications
- 出版年：2016
- 出版时间：17 June 2016
- 年：2016
- 卷：475
- 期：1
- 页码：140-148
- 全文大小：3049 K
文摘
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MiR-145a-5p promotes adipocytes proliferation.
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MiR-145a-5p is negatively correlated with obesity.
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MiR-145a-5p mediates adipocytes differentiation via regulating pathway related adipocytes differentiation.
MiR-145a-5p mediating adipocytes differentiation was regulated by DNA methylation.