Musk xylene induces malignant transformation of human liver cell line L02 via repressing the TGF-β signaling pathway

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• 作者：Youyu Zhang^a ; ^b ; ^{zhangyouyucxf@163.com} ; Lixing Huang^c ; ¹ ; Yujie Zhao^b ; Tianhui Hu^b ;
• 关键词：Musk xylene ; Carcinogenicity ; TGF-β
• 刊名：Chemosphere
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：168
• 期：Complete
• 页码：1506-1514
• 全文大小：6451 K
• 卷排序：168

文摘

Knowledge concerning the toxicity of MX is still limited. An affirmative effects of MX on cell malignant transformation was observed. The TGF-β signaling pathway might regulate the oncogenesis of MX.