Molecular prevalence of multiple genetic disorders in Border collies in Japan and recommendations for genetic counselling
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- 作者：K. Mizukami ; A. Yabuki ; M. Kohyama ; K. Kushida ; M.M. Rahman ; M.M. Uddin ; M. Sawa ; O. Yamato ; osam@vet.kagoshima-u.ac.jp" class="auth_mail" title="E-mail the corresponding author
- 关键词：Canine ; Border collies ; Genetic disorders ; Molecular prevalence ; Prevention
- 刊名：The Veterinary Journal
- 出版年：2016
- 出版时间：August 2016
- 年：2016
- 卷：214
- 期：Complete
- 页码：21-23
- 全文大小：181 K
文摘
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Mutant allele frequencies of seven genetic disorders in Border collies in Japan were examined.
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More than half of the dogs (56%) had no mutant alleles associated with the disorders.
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This finding suggests that these disorders can be removed from the population through selection.
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Reproductive management should be performed based on selection schemes appropriate to each disorder.