Metabolic profile of anhydrosafflor yellow B in rats by ultra-fast liquid chromatography/quadrupole time-of-flight mass spectrometry
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- 作者：Shijun Yue ; Liang Wu ; Jun Wang ; Yuping Tang ; yupingtang@njucm.edu.cn" class="auth_mail" title="E-mail the corresponding author ; Cheng Qu ; Xuqin Shi ; Pengxuan Zhang ; Yahui Ge ; Yujie Cao ; Hanqing Pang ; Chenxiao Shan ; Xiaobin Cui ; Li Qian ; Jin-ao Duan
- 关键词：Carthamus tinctorius ; Anhydrosafflor yellow B ; AHSYB ; Metabolic profile ; UFLC ; Qq-TOF&ndash ; MS/MS
- 刊名：Journal of Chromatography B, Analytical Technologies in the Biomedical and Life Sciences
- 出版年：2016
- 出版时间：1 March 2016
- 年：2016
- 卷：1014
- 期：Complete
- 页码：37-44
- 全文大小：1570 K
文摘
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Development of a UFLC/Qq-TOF–MS/MS method to study metabolism of AHSYB in rats.
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The metabolic profile of AHSYB was characterized in detail for the first time.
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A total of 22 metabolites and 11 metabolic pathways were found in vivo.
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The results provide essential data for understanding in vivo process of AHSYB and further study on it.