Dendritic cell inhibitory receptor 4 (DCIR4) is preferentially expressed on inflammatory and patrolling monocytes
详细信息 查看全文
- 作者：Yosuke Kameda1 ; Motoki Hanayama1 ; Atsushi Kishimoto ; Masahiko Kume ; Kazuo Yamamoto ; Naoki Matsumoto ; nmatsu@k.u-tokyo.ac.jp" class="auth_mail" title="E-mail the corresponding author
- 关键词：Monocytes ; Marker ; Monoclonal antibody ; Differentiation ; Lectin
- 刊名：Biochemical and Biophysical Research Communications
- 出版年：2016
- 出版时间：11 November 2016
- 年：2016
- 卷：480
- 期：2
- 页码：215-221
- 全文大小：2635 K
文摘
- •
A monoclonal antibody against mouse DCIR4 was established.
- •
DCIR4 is expressed on majority of monocytes with dichotomic expression levels.
- •
DCIR4Low cells are inflammatory monocytes.
- •
DCIR4High cells are patrolling monocytes.
- •
Differentiation of inflammatory monocytes to DCs diminishes DCIR4 expression.