Incidence and outcomes of bepridil-induced interstitial pneumonia

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• 作者：Kei Yamasaki ; Kazuhiro Yatera ; Shingo Noguchi ; Keishi Oda ; Kentarou Akata ; Chinatsu Nishida ; Toshinori Kawanami ; Yukiko Kawanami ; Hiroshi Ishimoto ; Shiro Ono ; Yukio Wakuta ; Hiroshi Mukae
• 关键词：Bepridil ; Drug-induced interstitial pneumonia ; Pulmonary toxicity
• 刊名：Respiratory Medicine
• 出版年：December, 2013
• 年：2013
• 卷：107
• 期：12
• 页码：2088-2091
• 全文大小：201 K

文摘

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Summary

Background

The incidence of bepridil-induced pulmonary toxicity, such as interstitial pneumonia, is still unknown. The aim of the present study was to evaluate the incidence of bepridil-induced pulmonary toxicity.

Methods and results

A total of 253 patients treated with bepridil between January 2009 and January 2011 were retrospectively evaluated. Eight out of the 222 evaluable patients (male/female: 5/3, age range: 64-97 years, average age: 80.5 years, median age: 81.0 years) showed bepridil-induced pulmonary toxicity.

Conclusions

The incidence of bepridil-induced pulmonary toxicity was 3.60% in our study population.