A Diencephalic Dopamine Source Provides Input to the Superior Colliculus, where D1 and D2 Receptors Segregate to Distinct Functional Zones
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- 作者：Andrew D. Bolton1 ; 4 ; andrew.d.bolton@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Yasunobu Murata1 ; Rory Kirchner1 ; Sung-Yon Kim2 ; Andrew Young1 ; Tru Dang1 ; Yuchio Yanagawa3 ; Martha Constantine-Paton1
- 刊名：Cell Reports
- 出版年：2015
- 出版时间：3 November 2015
- 年：2015
- 卷：13
- 期：5
- 页码：1003-1015
- 全文大小：5100 K
文摘
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RNA-seq describes dopamine-related gene expression in the superior colliculus (SC)
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D1+ and D2+ neurons segregate to functionally distinct SC layers
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D1+ and D2+ neurons in the SC differentially express the inhibitory marker VGAT
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Retrograde tracing points to A13 as the source of dopamine to the SC
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Patch-clamp analysis suggests functional consequences of SC dopamine