Synthesis of orthogonally protected l-glucose, l-mannose, and l-galactose from d-glucose

详细信息    查看全文

• 作者：Yangbing Li ; Zhaojun Yin ; Bo Wang ; Xiang-Bao Meng ; Zhong-Jun Li
• 关键词：Carbohydrates ; l-Hexoses ; Protecting groups ; Lattrell&ndash ; Dax method
• 刊名：Tetrahedron
• 出版年：2012
• 出版时间：26 August, 2012
• 年：2012
• 卷：68
• 期：34
• 页码：6981-6989
• 全文大小：878 K

文摘

An efficient route to orthogonally protected l-glucose, l-mannose, and l-galactose is described. Using the strategy to switch the functional groups at C1 and C5 of d-glucose, l-glucose is obtained via a key intermediate C-glycoside. Preparations of l-mannose and l-galactose derivatives from the orthogonally protected l-glucose were accomplished in good yields using the Lattrell-Dax method.