Real-time amperometric monitoring of cellular hydrogen peroxide based on electrodeposited reduced graphene oxide incorporating adsorption of electroactive methylene blue hybrid composites
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- 作者：Dongdong Zhang ; Xiaoyan Ouyang ; Lingzhi Li ; Bingling Dai ; Yanmin Zhang ; zhang2008@mail.xjtu.edu.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：Cellular hydrogen peroxide ; Graphene ; Methylene blue ; Electrochemistry ; Cancer cell ; Biosensor
- 刊名：Journal of Electroanalytical Chemistry
- 出版年：2016
- 出版时间：1 November 2016
- 年：2016
- 卷：780
- 期：Complete
- 页码：60-67
- 全文大小：1174 K
文摘
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2-D hybrid material was fabricated by electrodeposited reduced GO-MB onto GCE.
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The ERGO-MB/GCE was used as H2O2 biosensor for the electrochemical detection of H2O2 under physiological conditions.
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The H2O2 biosensor exhibits performance including high sensitivity and selectivity, broad linear range and quick response.
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The developed sensor could be well distinguished cancer cells from normal cells through H2O2 sensing.