- 作者：Abhishek Sharma ; Nathan Congdon ; Yang Gao ; Yaogui Lu ; Yanru Ye ; Jing Wu ; Dennis S.C. Lam ; Liping Li ; Jiasi Wu ; Yee Kit Tse ; Mingzhi Zhang ; Yue Song ; Sian Griffiths
- 刊名：American Journal of Ophthalmology
- 出版年：2010
- 出版时间：1 February 2010
- 年：2010
- 卷：149
- 期：2
- 页码：347-353.e1
- 全文大小：772 K
Purpose
To evaluate the hypothesis that changes in nutritional status could be partly responsible for observed increases in myopia prevalence among Chinese children.Design
Cross-sectional cohort study.
Methods
Rural Chinese secondary school children participating in a study of interventions to promote spectacle use were randomly sampled (20 % of children with uncorrected vision >6/12 bilaterally, and 100 % of remaining children) and underwent cycloplegic refraction with subjective refinement and measurement of height and weight. Stunting was defined according to the World Health Organization standard population.
Results
Among 3226 children in the sample, 2905 (90.0 % ) took part. Among 1477 children undergoing refraction, 1371 (92.8 % ) had height and weight measurements. These children had a mean age of 14.5 ± 1.4 years, 59.8 % were girls, and mean spherical equivalent refraction was −1.93 ± 1.82 diopters. Stunting was present in 87 children (6.4 % ). While height was inversely associated with refractive error (RE) (taller children were more myopic) among boys (r = −0.147, P = .001), this disappeared when adjusting for age, and no such association was observed among girls. Neither girls nor boys with stunting differed significantly in refraction from children without stunting, and neither stunting nor height was associated with RE when adjusting for age, height, and parental education. The power of this study to have detected a 0.75 diopters difference in RE between children with and without stunting was 0.96.
Conclusion
Results from this cross-sectional study are not consistent with the hypothesis that nutritional status is a determinant of RE in this setting.