Beneficial effects of cornel iridoid glycoside on behavioral impairment and senescence status in SAMP8 mice at different ages
详细信息 查看全文
- 作者：Denglei Ma ; Yanqiu Zhu ; Yanzheng Li ; Cuicui Yang ; Li Zhang ; Yali Li ; Lin Li ; linlixw@126.com" class="auth_mail" title="E-mail the corresponding author ; Lan Zhang ; lanizhg@126.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Cornel iridoid glycoside ; Aging ; SAMP8 ; Behavior ; Tau phosphorylation ; Alzheimer&rsquo ; s disease
- 刊名：Behavioural Brain Research
- 出版年：2016
- 出版时间：1 October 2016
- 年：2016
- 卷：312
- 期：Complete
- 页码：20-29
- 全文大小：2870 K
文摘
- •
CIG could not only treat early AD but also possess beneficial effects on moderate to severe AD.
- •
CIG has the potential effect to ameliorate the daily living qualities and the lifespan of AD patients.
- •
The pharmacological mechanism of CIG related to anti-hyperphosphorylation of tau in SAMP8 mice, which benefits to AD treatment.