Genome-wide miRNA screening reveals miR-310 family members negatively regulate the immune response in Drosophila melanogaster via co-targeting Drosomycin

详细信息    查看全文

• 作者：Yao Li^a ; Shengjie Li^a ; Ruimin Li^a ; Jiao Xu^a ; Ping Jin^a ; Liming Chen^b ; Fei Ma^a ; ^{mafei01@tsinghua.org.cn}
• 关键词：miR-310 family ; Innate immune response ; Toll signaling ; Drosomycin ; Drosophila melanogaster
• 刊名：Developmental & Comparative Immunology
• 出版年：2017
• 出版时间：March 2017
• 年：2017
• 卷：68
• 期：Complete
• 页码：34-45
• 全文大小：4132 K
• 卷排序：68

文摘

We investigated immune response in Drosophila infected with Gram-positive bacteria. Ninety-three immune-response-related miRNAs were identified. Eight of the miRNAs were involved in Toll-mediated immune response. miR-310 family members regulate the immune response by co-targeting Drosomycin.