Preparation of a nitric oxide imaging agent from gelatin derivative micelles

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• 作者：Mikio Tatsutomi ; Jun-ichiro Jo ; Yasuhiko Tabata ; ^{yasuhiko@frontier.kyoto-u.ac.jp}
• 关键词：Gelatin ; Polymer micelles ; Water-solubilization ; Fluorescent dye ; Nitric oxide ; Macrophages
• 刊名：Regenerative Therapy
• 出版年：2016
• 出版时间：December 2016
• 年：2016
• 卷：5
• 期：Complete
• 页码：64-71
• 全文大小：986 K
• 卷排序：5

文摘

DAR-4M has been limited to use in vivo due to the lack of water-solubility. DAR-4M was water-solubilized by the micelle formation with a hydrophobidized gelatin. DAR-4M micelles were effective to visualize NO-producing macrophages in vivo.