Effect of antibiotics on extracellular protein level in Pseudomonas aeruginosa
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- 作者：Eigo Takahashia ; b ; Jae Man Leeb ; Hiroaki Monb ; Yuuka Chiedaa ; Chisa Yasunaga-Aokia ; Takahiro Kusakabeb ; Kazuhiro Iiyamaa ; iiyama@grt.kyushu-u.ac.jp" class="auth_mail" title="E-mail the corresponding author
- 关键词：Pseudomonas aeruginosa ; Extracellular protein ; Tetracycline ; Kanamycin ; Alkaline protease
- 刊名：Plasmid
- 出版年：2016
- 出版时间：March-May 2016
- 年：2016
- 卷：84-85
- 期：Complete
- 页码：44-50
- 全文大小：416 K
文摘
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Increased amount of extracellular protein was detected in those Pseudomonas aeruginosa strains harbouring certain plasmids.
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Increased level of extracellular protein was detected in the presence of kanamycin or tetracycline.
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All antibiotics inhibited total activity of protease(s) except alkaline protease (AprA).
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Tetracycline and kanamycin interfered with AprA production.
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The effect of AprA on extracellular protein levels was limited.