Quantitative analysis of tivantinib in rat plasma using ultra performance liquid chromatography with tandem mass spectrometry
详细信息 查看全文
- 作者：Yan-li Baia ; yifuyuanbyl@126.com" class="auth_mail" title="E-mail the corresponding author ; Hong-chang Yuanb ; Dong-tao Zhangc ; Yuan Liuc ; Yin Zhangc
- 关键词：Tivantinib ; Rat ; UPLC&ndash ; MS/MS ; Plasma ; Pharmacokinetics
- 刊名：Journal of Pharmaceutical and Biomedical Analysis
- 出版年：2016
- 出版时间：15 July 2016
- 年：2016
- 卷：126
- 期：Complete
- 页码：98-102
- 全文大小：673 K
文摘
- •
First report of the determination of tivantinib in rat plasma by UPLC–MS/MS.
- •
Good linearity, sensitivity, precision and specificity were achieved.
- •
Rapid analysis turnaround time for pharmacokinetic studies.