A novel poly(deep eutectic solvent)-based magnetic silica composite for solid-phase extraction of trypsin
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- 作者：Kaijia Xua ; Yuzhi Wanga ; wyzss@hnu.edu.cn" class="auth_mail" title="E-mail the corresponding author ; Yixue Lia ; Yunxuan Lina ; Haibao Zhanga ; Yigang Zhoub
- 关键词：Poly deep eutectic solvent ; Magnetic silica microspheres ; Magnetic solid-phase extraction ; Trypsin
- 刊名：Analytica Chimica Acta
- 出版年：2016
- 出版时间：23 November 2016
- 年：2016
- 卷：946
- 期：Complete
- 页码：64-72
- 全文大小：2035 K
文摘
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A strategy for solid-phase extraction of trypsin based on poly(deep eutectic solvent) modified magnetic silica microspheres.
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Fe3O4@SiO2-MPS@PDES showed higher extraction capacity and selectivity on trypsin than Fe3O4@SiO2-MPS.
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The activity of the extracted trypsin was well retained.
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Practical application of Fe3O4@SiO2-MPS@PDES was evaluated.