Development of a more efficient hepatitis B virus vaccine by targeting hepatitis B virus preS to dendritic cells
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- 作者：Mingzhen Jinga ; jingmingzhen@whu.edu.cn" class="auth_mail" title="E-mail the corresponding author ; Jun Wanga ; wangjun2028@whu.edu.cn" class="auth_mail" title="E-mail the corresponding author ; Shengli Zhua ; jizaberu@hotmail.com" class="auth_mail" title="E-mail the corresponding author ; Fang Aoa ; aofang123@whu.edu.cn" class="auth_mail" title="E-mail the corresponding author ; Li Wanga ; fflashddd@163.com" class="auth_mail" title="E-mail the corresponding author ; Tao Hana ; doubleyingtao@163.com" class="auth_mail" title="E-mail the corresponding author ; Xin Yuea ; b ; bioyuexin@126.com" class="auth_mail" title="E-mail the corresponding author ; Ying Zhua ; yingzhu@whu.edu.cn" class="auth_mail" title="E-mail the corresponding author ; Linbai Yea ; Linbaiye@whu.edu.cn" class="auth_mail" title="E-mail the corresponding author ; Shi Liua ; liushi_liushi@whu.edu.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：Vaccine ; Hepatitis B virus ; preS ; Dendritic cells
- 刊名：Vaccine
- 出版年：2016
- 出版时间：20 January 2016
- 年：2016
- 卷：34
- 期：4
- 页码：516-522
- 全文大小：1107 K
文摘
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We developed a novel protocol for HBV vaccine production using the preS region.
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This novel vaccine makes use of the binding capacity of biotin and streptavidin.
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This vaccine has greater immunogenic potential than currently available vaccines.
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This novel vaccine exerts not only a prophylactic role but also a therapeutic role.