The 33-item Hypomania Checklist (HCL-33): A new self-completed screening instrument for bipolar disorder

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• 作者：Yuan Feng^a ; ^b ; ¹ ; Yu-Tao Xiang^c ; ^{xyutly@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Wei Huang^a ; ^b ; ^d ; ¹ ; Gang Wang^a ; ^b ; ¹ ; Lei Feng^a ; ^b ; Teng-Fei Tian^a ; ^b ; Ying Geng^a ; ^b ; Gabor S. Ungvari^e ; ^f ; Helen F.K. Chiu^g ; Ada W.Y. Tse^g ; Jules Angst^h ; ^{jules.angst@uzh.ch" class="auth_mail" title="E-mail the corresponding author}
• 关键词：Bipolar disorder ; Major depressive disorder ; Screening
• 刊名：Journal of Affective Disorders
• 出版年：2016
• 出版时间：15 January 2016
• 年：2016
• 卷：190
• 期：Complete
• 页码：214-220
• 全文大小：474 K

文摘

Bipolar disorder (BD) is often misdiagnosed as major depressive disorder (MDD). This study tested the psychometric properties and the accuracy of the Chinese version of the 33-item Hypomania Checklist (HCL-33) to identify BD in Chinese clinical settings.

Methods

A total of 350 depressed patients were consecutively interviewed in a major psychiatric hospital in China. The patients’ socio-demographic and clinical characteristics were recorded using standardized protocol and data collection procedures. The HCL-33 was completed by patients to detect symptoms characteristic of mania and hypomania. DSM-IV diagnoses were established using the Mini International Neuropsychiatric Interview (MINI).

Results

The HCL-33 showed high internal consistency with two-factorial dimensions. The optimal cut-off point on the HCL-33 to differentiate BD from MDD was 15, while cut-off points of 14 and 13 differentiated BD-I and BD-II from MDD, respectively. The maximum sensitivity was 0.62, 0.67 and 0.72 for differentiating BD, BD-I and BD-II from MDD, respectively.

Conclusions

The HCL-33 is a useful tool for screening for BD in Chinese depressed patients. The routine clinical use of the HCL-33 as a screening instrument for BD in Chinese patients is recommended.