Pre-clinical toxicity and immunogenicity evaluation of a MUC1-MBP/BCG anti-tumor vaccine
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- 作者：Boqi Hua ; b ; 1 ; Juan Wanga ; 1 ; Yingying Guoa ; Tanxiu Chena ; Weihua Nia ; Hongyan Yuana ; Nannan Zhanga ; Fei Xiea ; Guixiang Taia ; taiguixiang@163.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Mucin 1 ; BCG ; Anti-tumor ; Vaccine ; Toxicity ; Immunogenicity
- 刊名：International Immunopharmacology
- 出版年：2016
- 出版时间：April 2016
- 年：2016
- 卷：33
- 期：Complete
- 页码：108-118
- 全文大小：902 K
文摘
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MUC1–MBP/BCG anti-tumor vaccine is an immunotherapy that targets MUC1+ tumors.
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MUC1–MBP/BCG anti-tumor vaccine causes no obvious toxicity.
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MUC1–MBP/BCG anti-tumor vaccine induces a MUC1-specific Th1 immune response.
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MUC1–MBP/BCG anti-tumor vaccine induces a MUC1-specific IgG antibody response.