Subacute lesion volume as a potential prognostic biomarker for acute ischemic stroke after intravenous thrombolysis
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- 作者：Yohei Tateishi ; MD ; PhDa ; ytate.com@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Jumpei Hamabe ; MDa ; Tadashi Kanamoto ; MDa ; Kenjiro Nakaoka ; MDa ; Yoichi Morofuji ; MD ; PhDb ; Nobutaka Horie ; MD ; PhDb ; Tsuyoshi Izumo ; MD ; PhDb ; Minoru Morikawa ; MD ; PhDc ; Akira Tsujino ; MD ; PhDa
- 关键词：Ischemic stroke ; Tissue-type plasminogen activator ; Diffusion-weighted imaging ; Outcome
- 刊名：Journal of the Neurological Sciences
- 出版年：2016
- 出版时间：15 October 2016
- 年：2016
- 卷：369
- 期：Complete
- 页码：77-81
- 全文大小：215 K
文摘
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We assessed rates of good and poor outcomes at 90 days after tPA therapy.
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Outcomes were good (mRS score 0–1) and poor (4–6) outcomes and death.
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DWI lesion volumes at 7 days could predict good and poor outcomes at 90 days.
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The cut-off values for good and poor outcomes and death were 15 mL, 30 mL and 100 mL.
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We can predict outcome at 90 days by measuring subacute DWI lesion volume.