Macrophage-specific MafB inhibition deteriorated atherosclerotic plaque stability.
MafB inhibition did not affect atherosclerotic lesion area.
MafB inhibition was susceptible to macrophage apoptosis induced by oxidative stress.
MafB inhibition did not affect macrophage infiltration and efferocytosis.
MafB inhibition augmented expression of MMP-9 and inflammatory mediators.