Metabolomics evaluation of the in vivo toxicity of bromoacetonitriles: One class of high-risk nitrogenous disinfection byproducts

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• 作者：Yongfeng Deng ; Yan Zhang ; ^{yanzhang@nju.edu.cn} ; Yifeng Lu ; Kai Lu ; Hao Bai ; Hongqiang Ren ; ^{hqren@nju.edu.cn}
• 关键词：Disinfection byproducts ; Bromoacetonitriles ; Metabolomics ; Toxicity ; Mice
• 刊名：Science of The Total Environment
• 出版年：2017
• 出版时间：1 February 2017
• 年：2017
• 卷：579
• 期：Complete
• 页码：107-114
• 全文大小：1606 K
• 卷排序：579

文摘

Metabolomics was used to investigate the toxicity of BANs in mice. In vivo toxicity of BANs increased with the increasing number of bromine. BANs exposure disrupted metabolism of amino acid, energy, and lipid in mice.