Effects of vinpocetine and ozagrel on behavioral recovery of rats after global brain ischemia
详细信息 查看全文
- 作者：Wang Jincai ; Dong Tingfang ; tingfang_dong@163.com" class="auth_mail ; Zhang Yongheng ; Lu Zhongmin ; Zhai Kaihua ; Liu Xiaohong
- 关键词：Behavior ; Brain ischemia ; Ozagrel ; Pharmacology ; Rat ; Vinpocetine
- 刊名：Journal of Clinical Neuroscience
- 出版年：April, 2014
- 年：2014
- 卷：21
- 期：4
- 页码：661-663
- 全文大小：292 K
文摘
Brain ischemia leads to severe disruption of the nervous system and recovery is often prolonged. Rehabilitative post-ischemia pharmacological treatment may therefore be important for behavioral recovery, especially for cognition and motor behavior. The present study investigated the effects of combined vinpocetine and ozagrel administration on the behavioral recovery of rats from global brain ischemia. The results suggest that the combined treatment leads to significantly better improvement compared to single drug administration. We conclude that the combined use of vinpocetine and ozagrel may provide beneficial effects to patients suffering from brain ischemia.